Acquired von Willebrand’s syndrome as the first manifestation of juvenile-onset systemic lupus erythematosus with negative specific autoantibodies
نویسندگان
چکیده
Acquired von Willebrand’s syndrome (AvWS) is a rare heterogeneous bleeding disorder that could be secondary to many underlying diseases, among which systemic lupus erythematosus (SLE) is a less common cause. We presented an uncommon juvenile-onset SLE with AvWS as the first manifestation, whose autoantibodies were all negative except for low-titer positive antinuclear antibody (ANA). Initial corticosteroid treatment before the addition of immunosuppressant had poor effects. In conclusion, von Willebrand’s syndrome could be secondary to SLE and immunosuppressants are useful treatment for juvenile-onset AvWS secondary to SLE.
منابع مشابه
Acquired von Willebrand’s Syndrome in Systemic Lupus Erythematosus
T HE HEREDITARY NATURE of von Willebrand’s disease is well established and, although clinical manifestations are highly variable, most patients develop their initial hemorrhagic symptoms during early childhood. Acquired forms of von Willebrand’s disease have not been reported. The purpose of this report is to describe the unique combination of apparently acquired findings of von Wiflebrand’s di...
متن کاملAcquired von Willebrand’s Syndrome in Systemic Lupus Erythematosus
T HE HEREDITARY NATURE of von Willebrand’s disease is well established and, although clinical manifestations are highly variable, most patients develop their initial hemorrhagic symptoms during early childhood. Acquired forms of von Willebrand’s disease have not been reported. The purpose of this report is to describe the unique combination of apparently acquired findings of von Wiflebrand’s di...
متن کاملAcquired von Willebrand’s Syndrome in Systemic Lupus Erythematosus
T HE HEREDITARY NATURE of von Willebrand’s disease is well established and, although clinical manifestations are highly variable, most patients develop their initial hemorrhagic symptoms during early childhood. Acquired forms of von Willebrand’s disease have not been reported. The purpose of this report is to describe the unique combination of apparently acquired findings of von Wiflebrand’s di...
متن کاملAcquired von Willebrand’s Syndrome in Systemic Lupus Erythematosus
T HE HEREDITARY NATURE of von Willebrand’s disease is well established and, although clinical manifestations are highly variable, most patients develop their initial hemorrhagic symptoms during early childhood. Acquired forms of von Willebrand’s disease have not been reported. The purpose of this report is to describe the unique combination of apparently acquired findings of von Wiflebrand’s di...
متن کاملAcquired von Willebrand’s Syndrome in Systemic Lupus Erythematosus
T HE HEREDITARY NATURE of von Willebrand’s disease is well established and, although clinical manifestations are highly variable, most patients develop their initial hemorrhagic symptoms during early childhood. Acquired forms of von Willebrand’s disease have not been reported. The purpose of this report is to describe the unique combination of apparently acquired findings of von Wiflebrand’s di...
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